Hypha’s newsletter for Q4 2017 focusses on the selective production of N-oxide metabolites, especially relevant where there is potential for N-oxidation at multiple positions in the parent drug. We also discuss instability of some N-oxide metabolites and the impact of reversion back to the parent.
Q2 2026 – PROTAC MetID focus
Q2 2026 newsletter – PROTAC MetID focus From tackling the metabolism of PROTACs to synthesising oxidised metabolites, our latest newsletter features a MetID study undertaken
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