Unusual Gut Metabolites
November 17, 2023 11:06 am Leave your thoughtsUnusual gut metabolites For drugs that are locally acting, prominent metabolites in the target organ may be just as significant...
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Unusual gut metabolites For drugs that are locally acting, prominent metabolites in the target organ may be just as significant...
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Missing metabolites Accounting for metabolites is a key activity in drug development programs. Sometimes biotransformations result in metabolites that might...
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Unusual biotransformation reactions uncovered by scientists at Genentech This compilation of 10 case studies arising from work done at Genentech...
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MetID Guided Drug Design MetID guided target design is the topic of our paper pick for February, published by...
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Metabolism of de novo-designed macrocyclic drugs approved by the FDA By Julia Shanu-Wilson To date, only 4% (67) of FDA...
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Metabolites that Matter – Ivermectin Ivermectin is a natural product derived broad spectrum antiparasitic drug, primarily deployed to combat parasitic...
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Breaking C-F bonds in drugs – metabolism mediated release of fluorine By Samuel Coe and Julia Shanu-Wilson Fluorine is a...
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Hypha’s Q2 2023 Newsletter – acyl glucuronides, hydroxylated metabolites and our latest blogs In our Q2 2023 newsletter we look...
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Metabolism of 2022 FDA approved small molecule drugs part 2 Mixing it Up By Julia Shanu-Wilson In Part 1 of...
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Molecules that Matter – Rezafungin Rezafungin is an echinocandin with a chemical modification that confers high stability, a longer half-life,...
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