Frank will be giving a presentation at the EFMC-ISMC 2021 meeting on “Integration of Biocatalysis into Medicinal Chemistry Programs for...
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We’re proud of our scientists for the recent successful delivery of a client project. Metabolites of two drug substances were...
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Metabolism of PROTACs An understanding of the metabolism of PROTACs is a growing need since their metabolism can’t be readily...
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Metabolic pathways and disposition of Tropifexor in humans Looking at the structure of tropifexor, a farnesoid X receptor (FXR) agonist...
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Metabolism and disposition of ozanimod in humans Check out the implications of the complex metabolism of ozanimod discussed in a...
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Successful and Unsuccessful Prediction of Human Hepatic Clearance for Lead Optimization Here’s a great paper published by Jasleen Sodhi and Leslie Benet...
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Issues resulting from late-occurring and persistent human metabolites Issues in metabolite identification in dossiers submitted to the regulatory authorities are...
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We always really appreciate receiving feedback from a client. This time we celebrate project success for Alkermes for whom we used...
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Our newsletter for Q1 2021 features a commentary on the perceived increase in requests to access N-glucuronides, as well as...
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Project Manager and Head of Chemistry Richard Phipps, together with Hypha scientists Renia Gemmell, Chloe Herring and Chris Drake have received great feedback for the...
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